Home Login

PHARMACIST EVALUATING EXAMINATION SYLLABUS PHARMACEUTICAL SCIENCES PART 2

Categories: WORLD EDUATION NEWS

PHARMACIST EVALUATING EXAMINATION SYLLABUS PHARMACEUTICAL SCIENCES PART 2

  • Pharmaceutics and Drug Delivery Systems
  • Phamacokinetics and Biopharmaceutics
  • Medicinal Chemistry
  • Pharmacology
  • Toxicology and Clinical Toxicology
  • Biotechnology and Pharmacogenetics

PHARMACEUTICS AND DRUG DELIVERY SYSTEMS

In this course of study, the emphasis is on physico-chemical properties related to the design and formulation of dosage forms and optimal delivery of drugs to a site of action for therapeutic usefulness. This includes the role of biopharmaceutics, pre-formulation principles, drug stability and physical pharmacy in the development of safe and effective dosage forms. Bioequivalence, routes of administration and new design innovations are included.

TOPICS OF STUDY: PHARMACEUTICS & DRUG DELIVERY SYSTEMS

Solids and Solid Dosage Forms

The solid state

  • Bonding - Van der Waal’s, hydrogen, covalent, electrostatic, metallic crystal systems and habits
  • Crystallization - saturated and supersaturated solutions, crystal growth
  • Crystallinity - amorphous solids, degree of crystallinity, crystal defects
  • Polymorphism - effects on formulation, bioavailability
  • Hydrates and solvates - hygroscopicity, deliquescence, phase diagrams, effects on formulation, bioavailability, lyophilization Eutectic mixtures, solid solutions, clathrates and inclusion compounds

Solid dosage forms

  • Properties of powders, handling of powders, drying, mixing and milling
  • Particle size analysis - definitions, methods
  • Tableting - excipients and formulation, methods of granulation, tablet
  • compression
  • Tablet coating - methods and types of coating
  • Capsules - hard gelatin, soft gelatin, non-gelatin based capsules, formulation
  • Evaluation tests - uniformity of weight, content, dissolution, disintegration, hardness, friability
  • Sustained/controlled release - formulation, effect on bioavailability
  • Effervescent powders and tablets - formulation, storage

Solutions and Solubility

Thermodynamics of pharmaceutical solutions

  • 1st law, enthalpy, work
  • 2nd law, entropy
  • Gibbs free energy and chemical potential
  • Phase equilibria

Pharmaceutical solvents

  • Waters, alcohols, hydroalcohols, cosolvents

Aqueous and non-aqueous solutions

  • Syrups, elixirs, tinctures, collodions, spirits, liniments

Solvent/solute interacation

  • Intermolecular bonding, functional groups, prediction of drug solubility in water

Liquid-liquid solutions

  • Ideal and non-ideal solutions, Raoult’s law, partial miscibility

Solid-liquid solutions

  • Colligative properties, solutions of electrolytes and non-electrolytes, ionic equilibria, buffers, isotonicity

Gas-liquid solutions

  • Solubility of gases, Henry’s law.

Factors affecting solubility

  • pH, pKa, salts, temperature, esterification, complexation, solubilization, particle size, cosolvency, polarity, solubility parameters

Dissolution

  • Theory, methods of measuring dissolution rate, factors affecting dissolution rate
  • Hixon-Crowell Cube-Root Relation, Noyes-Whitney equation
  • Types of dissolution apparatuses
  • USP Dissolution monographs and acceptance criteria in vitro-in vivo correlation

Partition

  • Fick’s first and second laws, Nernst distribution law, pH-partition theory
  • steady state and non-steady state diffusion

 

Top articles
What the GRE Test Is and How to Prepare Published at:- What Is a Good GRE Score for Graduate School Admissions? Published at:- Why Perfect GRE Scores Aren't Usually Necessary Published at:- Advice for Law School Hopefuls About the GRE Published at:- Compare GRE Scores to LSAT Scores by Percentile Published at:- What is GRE?All About the GRE TEST(Introduction) Published at:- Should you take the GRE test?GRE exam is an ideal choice for you as: Published at:- GRE General Test Structure:The overall testing time for the GRE General Test is about three hours and 45 minutes. There are six sections with a minute break following the third section. Published at:- Manhattan Review GRE Preparation Home:Why Manhattan Review is the Best GRE Prep Option Available Published at:- Best GRE Instructors in the Industry:Prospective Manhattan Review Published at:- History of Manhattan Review Published at:- GRE 2021 Eligibility criteria – Are you eligible to take the GRE? Published at:- Over 100 International Students Allowed to Return to Their Chinese University Published at:- What is the PEBC Exam Published at:- What are the requirements of PEBC exams for CANADIAN GRADUATES,U.S. GRADUATES and INTERNATIONAL GRADUATES Published at:- Pharmacist Evaluating ExamWhy PEBC is important for Indian pharmacy students Published at:- Pharmacist Evaluating Examination sample question Biomedical sciences PART 1 Published at:- Pharmacist Evaluating Examination sample question Published at:- Pharmacist Evaluating Examination sample question Biomedical sciences PART 1 Published at:- Pharmacist Evaluating Examination sample question Biomedical sciences PART 1 Published at:- Pharmacist Evaluating Examination sample question Biomedical sciences PART 1 Published at:- Pharmacist Evaluating Examination sample question Biomedical sciences PART 1 Published at:- Pharmacist Evaluating Examination sample question Biomedical sciences PART 1 Published at:- Pharmacist Evaluating Examination sample question Biomedical sciences PART 1 Published at:- Pharmacist Evaluating Examination sample question Biomedical sciences PART 1 Published at:- Pharmacist Evaluating Examination sample question Biomedical sciences PART 1 Published at:- MCQs on Pharmacy Evaluating Examination Published at:- MCQs on Pharmacy Evaluating Examination Published at:- Pharmacist Evaluating Examination sample question MCQs PART 2 Published at:- Pharmacist Evaluating Examination sample question MCQs PART 2 Published at:- Pharmacist Evaluating Examination sample question MCQs PART 3 Published at:- Pharmacist Evaluating Examination sample question PART 4 Published at:- Pharmacist Evaluating Examination sample question MCQs PART 5 Published at:- For what reason is the GRE Troublesome and What Makes this Test so Hard Published at:- A few focuses have makes the GRE test hard Published at:- GRE Introduction to the Logical Writring Section 1 Published at:- GRE Introduction to the logical Writring Section 2 Published at:- GRE Verbal Thinking and Quantitative Thinking Published at:- GRE Introduction to the Logical Writring Section 3 Published at:- GRE Introduction to the Analytical Writing Measure SECTION 2 Published at:- GRE Prologue to the Scientific Composing Measure and Grasping the Setting for Writing Section 4 Published at:- GRE Introduction to the Verbal Segment 1 Published at:- GRE Introduction to the Quantitative Thinking Measure Published at:- Directions for Verbal Thinking and Quantitative Thinking Segments Published at:- GRE verbal practice paper segment 1 and answers given in block letter Published at:- GRE verbal practice paper segment 2 and answers given in block letter Published at:- Great many understudies in El Salvador benefit from bitcoin BTC training Published at:- PHARMACIST EVALUATING EXAMINATION SYLLABUS PHARMACEUTICAL SCIENCES PART 2 Published at:- GRE Verbal Practice Test question paper with answer Set 1 Published at:-
Main Category
Education Health
|| Java || Technology || US Education News || Others || Spring || PROGRAMMING LANGUAGE || NEW SCHEMES || Education || UK EDUCATION NEWS || US EDUCATION GRADE 9 || WORLD EDUATION NEWS || UNITED STATE COMPUTER EDUCATION || PEBC Exam Canada || Software Engineering || science education || GRE QUESTION PAPER || History || Health ||
closeConn($conn); ?>