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Pharmacist Evaluating Examination sample question Biomedical sciences PART 1

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Pharmacist Evaluating Examination sample question Biomedical sciences PART 1

The Pharmacy Examining Board of Canada

PHARMACEUTICAL SCIENCES

42 .The carbonic anhydrase inhibitor dorzolamide is structurally classified as a:

  1. biguanide.
  2. butyrophenone.
  3. sulfonamide.
  4. sulfonylurea.
  5. thiazolidinedione.

43 .Which of the following statements is FALSE regarding virus vectors used in the production of

biotechnology drugs?

  1. Viruses can be introduced by nutrients.
  2. Viruses can be generated by an infected production cell line.
  3. The most frequent source of virus introduction is the growth media.
  4. Viruses can be inactivated by physical or chemical treatment of the product.
  5. There is a trend toward using better-defined growth media in which serum levels are significantly

reduced.

44 .Which of the following excipients is NOT commonly found in biotechnology formulations?

  1. Albumin
  2. Lysine
  3. Tween 20
  4. Saline
  5. Phosphate

45 .An angiotensin-converting enzyme (ACE) inhibitor for which both renal elimination and metabolism

are important in the elimination of the drug and its active metabolites is:

  1. enalapril.
  2. fosinopril.
  3. lisinopril.
  4. quinapril.
  5. ramipril.

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