Pharmacist Evaluating Examination sample question Biomedical sciences PART 1
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Pharmacist Evaluating Examination sample question Biomedical sciences PART 1
The Pharmacy Examining Board of Canada
PHARMACEUTICAL SCIENCES
46 .Once daily dosing of aminoglycosides is effective due to:
- prolonged residence of the antibiotic in the body.
- post-antimicrobial effect.
- enhanced tissue accumulation.
- reduced renal clearance.
- higher peak-trough differences.
47 .How much NaCl is required to make 100 mL of isotonic 0.5% phenylephrine HCl solution? (NaCl
equivalent of phenylephrine HCl is 0.32)
- 100 mg
- 300 mg
- 500 mg
- 740 mg
- 900 mg
48 .Which of the following nonparenteral routes of administration yields the best bioavailability of
biotechnology protein drugs?
- Oral
- Rectal
- Ocular
- Pulmonary
- Transdermal
49 .Theoretically, the shelf life of a pharmaceutical tablet preparation is best measured by a change in
which of the following?
- Permeability of the drug
- Dissolution of the drug
- Strength of the drug
- Solubility of the drug
- Partitioning of the drug
50 .A drug that is considered to be low clearance and is metabolized entirely by the liver is sensitive to
changes in:
- drug binding to plasma proteins.
- bile secretion.
- hepatic blood flow.
- renal blood flow.
- p-glycoprotein transport activity.